L-Valine
L-Valine
View documents (PDF) of following L-Valine information.
TDS
SDS

DESCRIPTION

L-VALINE: AN INDISPENSABLE AMINO ACID FOR GROWTH PERFORMANCE AND YOUR BOTTOM LINE

Through a series of trials, AJINOMOTO ANIMAL NUTRITION EUROPE has observed that piglet performance is significantly improved when diets are balanced with L-Valine (Figure 1). For piglets, the optimum ratio of digestible Valine-to-Lysine is 70% for optimum growth. Though Valine is also limiting for broilers, the optimum recommended ratio between digestible Valine and lysine is 77%.

 

The commercial availability of L-Valine has allowed nutritionists to balance the amino acid content of swine and poultry feeds, meet the amino acid requirements of their high-yielding livestock without causing an imbalance in other amino acids, and significantly reduce the nitrogen excretion of their livestock through a reduction in dietary protein (Figure 2). Together, L-Valine provides the feed industry with a tool that can meet a variety of economical, nutritional and environmental targets:

Lower feed cost 
  • Better dietary amino acid balance (less waste)
  • Lower nitrogen excretion from animals into the environment

 

TDS

Commercial Guarantee
L-Valine content: 96.5% minimum

Physical Data
Chemical formula: C5H11NO2
Molecular weight1: 117.15
Appearance: Whitish crystalline powder
Purity: 96.5% (on an as is basis); 98.0% (on a dry matter basis)
Dry matter: 98.5% (Minimum)
Bulk Density: 0.5 to 0.6 grams/cm3 (31.2 to 37.5 lbs/ft3)
Total nitrogen1: 11.54% (on an as is basis)
Crude protein (%/16 g-N1): 72.13% (on an as is basis)
Calculated energy:
Swine, DE / 5,830 (kcal/kg) / 2,644 (kcal/lb)
Swine, ME / 5,480 (kcal/kg) / 2,486 (kcal/lb)
Swine, NE / 4,235 (kcal/kg) / 1,921 (kcal/lb)
Poultry, ME / 5,260 (kcal/kg) / 2,386 (kcal/lb)

Stability
Shelf life: 2 years (25 kg Bags) when unopened and stored under recommended conditions

Packaging Specifications
Valine 25 kg bags
:
Pallet weight – 2,204 lbs (1,000 kg)
Pallet size – 39” x 47” (1.00 m x 1.20 m)
Stack pattern – 5 bags/layer, 8 bags high (40 bags / pallet)
Pallet dimensions (stacked) – 39” Wide, 47” Deep, 59” High (1.00 m x 1.20 m x 1.50 m)

1 The Merck Index, 14th Edition (2006), L- Threonine (9909; Pg. 1703)
‡ These values are for informational purposes only and do not constitute any commercial guarantee

SDS

Manufactured By:
Ajinomoto Animal Nutrition Europe SAS
Paris, France

Distributed By:
Ajinomoto Animal Nutrition North America, Inc.
1116 Hwy 137
Eddyville, Iowa 52553

Emergency Phone:
(641) 969-4551 – Eddyville, IA
(773) 380-7000 – Chicago, IL

1. IDENTIFICATION OF THE SUBSTANCE/MIXTURE AND OF THE COMPANY
1.1. Product identifier
Trade Name: L-Valine Feed Grade
1.2. Relevant identified uses of the product
Indentified uses: This product shall exclusively be used in animal nutrition. It shall not be used for any food application
1.3. Identification of the Company
Manufacturing Company:
Ajinomoto Animal Nutrition Europe SAS
153, rue de Courcelles
75817 PARIS CEDEX 17 – FRANCE
Telephone number: +33 1 44 40 12 12
Telefax: +33 1 44 40 12 13
Email: Infos_FDS@eli.ajinomoto.com
1.4. Emergency telephone number +33 3 22 54 70 00

2. HAZARDS IDENTIFICATION
2.1. Classification of the mixture
Classification according to Regulation (EC) No 1272/2008 [EU-GHS/CLP]
This product is not classified according to Regulation (EC) No 1272/2008.
Classification according t Directive 67/548/EEC
This product is not classified according to Directive 67/548/EEC
2.2. Label Elements
Labeling according to regulation (EC) No 1272/2008 [EU-GHS/CLP]

Pictogram (s): -
Signal Word: -
Hazard Statement: -
Precautionary Statement Prevention: -
Precautionary Statement Response: -
Precautionary Statement Storage: -
Precautionary Statement Disposal: -
Labeling according to Directive 67/548/EEC
Symbol (s): -
Risk phrase (s): -
Safety advice: -
2.3. Other Hazards
None

3. COMPOSITION/INFORMATION ON INGREDIENTS

Components Classification Concentration
L-Valine
α-Aminoisovaleric acid
(S)-2-Amino-3-methylbutanoic acid
L-Val, C5H11NO2
No CAS: 72-18-4 - >96.5% (as is) &
No EINECS: 200-773-6 - >96.5% (dry matter basis)
No Index: - - >96.5% (dry matter basis)

4. FIRST AID MEASURES
4.1. Description of first aid measures
General advices
No data available
If inhaled
In case of breathing trouble, immediately relocate to a fresh air environment. Rinse mouth with water. If not breathing, give artificial respiration. If breathing becomes difficult, give oxygen and seek medical attention.
In case of skin contact
In case of exposure, wash with soap and copious amounts of water. If irritation persists, seek medical attention.
In case of eye contact
Flush eyes with copious amounts of water for at least 15 minutes. Ensure adequate flushing by separating eyelids with fingers. If contact lenses are worn, remove lenses and continue rinsing. Seek medical attention.
If swallowed
Rinse mouth with water. If any trouble appears, seek medical attention.
4.2. Most important symptoms and effects, both acute and delayed
No data available
4.3. Indication of any immediate medical attention and special treatment needed
No data available

5. FIREFIGHTING MEASURES
5.1. Extinguishing media
Water spray, carbon dioxide, dry chemical powder/foam.
5.2. Special hazards arising from substance or mixture
No data available
5.3. Advice for firefighters
Wear protective clothing and breathing mast to protect from fumes
5.4. Further information
No data available

6. ACCIDENTAL RELEASE MEASURES
6.1. Personal precautions, protective equipment and emergency procedures
Wear a mask. (See paragraph 8).
6.2. Environmental precautions
In case of release in large quantities, avoid releasing in sewers and water courses.
6.3. Methods and materials for containment and cleaning
Prevent spills from entering sewers and water courses.
Avoid dust generation and ventilate the area. Collect the product and place it in bags or containers for later disposal and elimination as waste, according to local legislation. After material has been removed, rinse the spill site with water.

7. HANDLING AND STORAGE
7.1. Precautions for safe handling
Follow good manufacturing practice and personal hygiene.
Standard precautions for powdered products or products generating dust:
  -  Avoid dust dispersion during grinding or blending operations
  -  Provide mechanical exhaust or ventilation
  -  Clean and eliminate dust from equipment regularly
  -  Use anti-static equipment
  -  Avoid heat sources and sparks.
7.2. Conditions for safe storage, including any incompatibilities
Storage in the bags in which the product has been delivered.
Keep in dry conditions.
Keep away from electric sparks and heat sources.
7.3. Specific end uses
No data available

8. EXPOSURE CONTROLS/PERSONAL PROTECTION
8.1. Control Parameters
Components with workplace control parameters
Does not contain any substance subject to an exposure limit value.
8.2. Exposure controls
Engineering controls
No data available
Personal protective equipment

Eye/face protection Wear safety goggles in case of direct contact
Body protection Wear protective clothes covering skin. Discard or wash protective clothes after exposure to dust of the product.
Skin protection Wear gloves, especially in case of extended contact
Respiratory protection Wear a (paper) mask covering nose and mouth.

9.1. Information on basic physical and chemical properties

Appearance White powder
Odor No data available
Odor Threshold No data available
pH 5 to 6 (5% solution)
Melting point / freezing point 315°C (closed capillary), then sublimes
Initial boiling point and boiling range No data available
Flash point No data available
Evaporation rate No data available
Flammability (solid, gas) No data available
Upper / lower flammability or explosive limits No data available
Vapor pressure No data available
Vapor density 0.5 to 0.6
Water solubility At 0°C: 83.4 g/L
At 25°C: 88.5 g/L
At 50°C: 96.2 g/L
At 65°C: 102.4 g/L
Partition coefficient: n-octanol / water Log Pow = -2.30
Auto ignition Between 10mJ and 30mJ
Decomposition temperature 315°C
Self-ignition temperature >400°C (layer)
Viscosity No data available
Explosive properties Explosion maximal overpressure: 5.7 bar
Maximum explosion pressure rise: 507 bar.s-1
Kst: 138 bar.m/s-1
The product is classified in ST1 class
Oxidizing properties No data available
9.2. Other safety information
No data available

10. STABILITY AND REACTIVITY
10.1. Reactivity
Exothermic reaction between 340°C and 360°C
10.2. Chemical stability
Stable for 2 years if stored in recommended conditions.
10.3. Possibility of hazardous reactions
No data available
10.4. Conditions to avoid
Avoid electrostatic sparks and ignition sources.
10.5. Incompatible materials
No data available on incompatible materials.
10.6. Hazardous decomposition products
When heated to decomposition, carbon and nitrous oxides will be emitted.

11. TOXICOLOGICAL INFORMATION
11.1. Acute toxicity
Acute oral toxicity: Not toxic when ingested: acute oral LD50 > 2000mg/kg in rat.
Acute inhalation toxicity: Not toxic when inhaled: LC50 ≥ 5.26 g/m3 in rat.
11.2. Skin corrosion / irritation
Not irritating to (human) skin (according to EC standards, OJEC, L 110 A, Vol 36, 4 May 1993)
11.3. Serious eye damage / eye irritation
Not irritation to (human) eyes (according to EC standards, OJEC, L 110 A, Vol 36, 4 May 1993).
11.4. Respiratory or skin sensitization
Not sensitizing for the skin (LLNA test)
11.5. Germ cell mutagenicity
Not mutagenic (Bacterial reverse mutation test, Gene nutation test at the TK-locus of L5178Y cells, Chromosomal aberration test in cultured Chinese hamster Ovary (CHO) cells). In vitro micronucleus test in cultured human lymphocytes, Bone marrow ('in vivo') micronucleus test incorporated in a repeated-dose (13 week) oral toxicity study in rats.
11.6. Carcinogenicity
Not carcinogenic
11.7. Reproductive toxicity
To the best knowledge of Ajinomoto Animal Nutrition Europe, no effect on foetal development.
11.8. Specific target organ toxicity – single exposure
No data available
11.9. Specific target organ toxicity – repeated exposure
No data available
11.10. Aspiration hazard
No data available
11.11. Signs and symptoms of exposure
No data available
11.12. Additional information
NOAEL (No adverse effect level, oral administration) is conservatively: 628 mg/kg bw (90 days ingestion in rats).

12. ECOLOGICAL INFORMATION
12.1. Toxicity
Not toxic for animal and plant.
12.2. Persistence and degradability
Biodegradable
12.3. Bioaccumulative potential
None.
12.4. Mobility in soil
No data available.
12.5. Results of PBT and vPvB assessment
No data available
12.6. Other adverse effects
When a large quantity of the product is released in a river or waste treatment plant, the ecosystem or the functioning of the plant may be disturbed due to increased demand in oxygen required to degrade the product (increase of the biological oxygen demand – BOD - of water)

13. Disposal Consideration
Waste treatment methods
Treat wastes in accordance with the local // national legislation.

14. Transport Information
14.1. UN Number
ADR / RID: -     IMDG: -     IATA: -
14.2. UN proper shipping name
ADR / RID: -     IMDG: -     IATA: -
14.3. Transport hazard class (es)
ADR / RID: -     IMDG: -     IATA: -
14.4. Packing group
ADR / RID: -     IMDG: -     IATA: -
14.5. Environmental hazards
ADR / RID: No     IMDG Marine pollutant: No     IATA: No
14.6. Special precautions for user
No data available

15. REGULATORY INFORMATION
15.1. Safety, health and environmental regulations / legislation specific for the substance or mixture
This product is within the scope of Regulation (EC) No 1831 / 2003 of 22 / 09 / 2003 on additives for use in animal nutrition (OJ EU n◦ L 268 of 18 / 10 / 2003).
15.2. Chemical Safety Assessment
No data available

16. OTHER INFORMATION
References
The Merck Index 13th edition. Merck and Co., 2001

Partition coefficient (n-octanol / water): TNO Quality of Life, Zeist, The Netherlands. Report to Ajinomoto Animal Nutrition Europe No V8947 / 09 (15 July 2010).
Particle size distribution & Dusting potential: TNO Nutrition and Food Research, Zeist, The Netherlands, BCV_05_0292 / SMC (2005).
Flammability, explosion characteristics,
auto-ignition, etc.:
INERIS. Study report ot Ajinomoto Animal Nutrition Europe No 76597, 12 July 2006.
Acute oral toxicity: TNO Nutrition and Food Research, Zeist, The Netherlands. Report to Ajinomoto Animal Nutrition Europe No V6210 / 04, 2005
Acute 4-hour toxicity study in rat: TNO Nutrition and Food Research, Zeist, The Netherlands. Report to Ajinomoto Animal Nutrition Europe No V6201 / 08, 4 Oct 2005.
Skin and eye
Irritation / corrosion:
TNO Nutrition and Food Research, Zeist. The Netherlands. Reports to Ajinomoto Animal Nutrition Europe No V6211 / 03 (June 2005) and No V6215 / 14 (June 2005).
Skin sensitization: TNO Nutrition and Food Research, Zeist, The Netherlands. Report to Ajinomoto Animal Nutrition Europe No V6496, 27 Sept. 2005
Mutagenicity: TNO Nutrition and Food Research, Zeist, The Netherlands. Reports to Ajinomoto Animal Nutrition Europe V6205 / 06 (2005), No V6202 / 02 (2005) and No V6203 / 04 (2005).
Sub-chronic toxicity: TNO Nutrition and Food Research, Zeist, The Netherlands. Report to Ajinomoto Animal Nutrition Europe No V6357, (2006) Tsubuku and al. 2004 International Journal of Toxicology, vol. 23, pp. 119-126
Prenatal developmental toxicity: TNO Nutrition and Food research, Zeist, The Netherlands. Report ot Ajinomoto Animal Nutrition Europe No V6306 (2005).

Disclaimer of responsibility
The present information sheet was created voluntarily. The pieces of information contained in this document come from sources we consider as reliable. Nevertheless, they are supplied without any guarantee, explicit or implicit, of their accuracy. The conditions or methods for handling, storage, use or disposal of the product are out of our control and may fall out of the scope of our competence. For this reason, among others, we decline any liability in case of loss, damage or cost resulting of or linked to, in any manner, the handling, storage, use or disposal of the product. This present information was written and shall be used only for this product. Were this product used as a constituent of another product, information contained in this sheet may no longer apply.

The information contained herein is correct to the best of our knowledge. The recommendations or
suggestions made in this document are made without guarantee or representation as to result.

For animal feed only – not for human consumption.